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Oprah Winfrey hosts a sit-down conversation around the radical impact of prescription weight loss medications in the primetime event, "An Oprah Special: Shame, Blame and the Weight Loss Revolution," airing MONDAY, MARCH 18 (8:00-9:00 p.m. EDT), on ABC and the next day on Hulu. The special delves into the prevailing questions and concerns surrounding the impact on our health care, economy, lifestyle and culture.